ICSI-Conceiving Is Possible!

Having a baby is a blessing. To become parents is a dream come true. But sometimes certain hurdles stop you from making your dream come true. One of the reasons could be the fertility issues in male members. Infertility in men is caused due to non-functioning sperms. This condition can be treated with medical treatments. One of the treatments to solve this condition is ICSI (Intra-Cytoplasmic Sperm Injection).

Intra Cyto Sperm Injection

Intra-Cytoplasmic Sperm Injection also known as ICSI treatment is a type of Assisted Reproductive Technology (ART) to treat male infertility problems. It is a part of the In Vitro Fertilization (IVF) treatment. ICSI is similar to IVF where gametes (eggs and sperm) are collected from each partner. What makes ICSI different from IVF is the method of achieving fertilization ICSI is a micro fertilization technique where only a single sperm is used and inserted into a mature egg, which is later placed in a woman’s uterus after fertilization.

Why ICSI Infertility Treatment?

Opting for an ICSI treatment is beneficial because unlike IVF the sperm does not have to travel to the egg nor does it have to penetrate it to fertilize it. ICSI is a type of IVF treatment used for couples with male factor infertility. This is an effective method because it includes injecting a sperm straight into the egg for fertilization. Here, the sperm fertilizes the egg on its own in the laboratory. ICSI Treatment in Nepal is the top solution for treating male infertility.


ICSI is recommended as the best option when:

  • The treatments like Intra Uterine Insemination or In Vitro Fertilizations have failed
  • The patients want to have their own baby with their own contributions and not by any surrogates or donors

Indications of ICSI :

ICSI is recommended for:

  • Sperm count less than 15-20 million per millimetre
  • Ejaculation problems
  • Low sperm morphology i.e. abnormal shaped sperms
  • Low sperm motility i.e. abnormal movement less than 35%
  • Frozen sperms
  • Surgically retrieved sperms
  • Failure of IVF
  • ICSI is a boon to couples with lower egg production at the stage of egg retrieval as it produces an increased percentage of fertilized eggs

In the procedure of ICSI in Nepal, both fresh and frozen sperms are used. A process called micromanipulation where a single sperm is picked up and injected directly into the egg is used. The procedure of ICSI in Nepal will last for around four to six weeks.

The Procedure of ICSI Treatment

ICSI Treatment in Nepal is performed by the highly skilled and experienced fertility experts. It is done by conducting the IVF treatment first to create an embryo in the laboratory. When the sperms fail to penetrate the eggs naturally and fertilization doesn’t take place, the best quality sperm is selected and picked manually using techniques like Percutaneous Epididymis Sperm Aspiration (PESA), or Testicular Sperm Aspiration (TESA) where the surgeon uses a small needle to extract the sperms from the stored area and inserted into the egg with a specialized pipette. After fertilization in the lab, the embryo created is implanted into the intended mother’s womb.


ICSI treatment is conducted when the In Vitro fertilization process fails. ICSI is conducted under the supervision of experts.

  • First, the Ovary stimulation is done by using fertility drugs
  • The eggs are retrieved surgically from the mother
  • Sperm extraction either by ejaculation or by manual techniques like PESA or TESAICSI Procedure
  • The mature egg is held with a special pipette or micromanipulator
  • A single sperm is immobilized and picked up with a delicate, sharp, and hollow injection needle
  • The needle carefully inserted into the cytoplasm of the egg
  • After injecting the sperm into the egg, the needle is removed
  • The sperm injected egg will be kept in the lab for observation and monitored for fertilization, which forms a Blastocyst
  • The developing embryo or the Blastocyst will be transferred into the uterus of the mother for conception

After the embryo transfer, you need to re-visit the ICSI Centre after two weeks for the pregnancy test. If your pregnancy test is positive, then it will work as regular pregnancy and you will be advised to avoid lifting heavy objects, hard exercise, etc.

Is ICSI different from IVF?

Both ICSI and IVF are intended towards achieving a single goal of conceiving. Both of them are objected towards treating fertilization problems and help the couple to conceive. Yet, the method used, the procedure followed are different from each other.


The treatment of ICSI in Nepal is more successful than the IVF. ICSI differs from IVF because:IVF is done when the woman is facing infertility problems whereas, ICSI is done when the infertility problem is with the male member

  • IVF involves manipulation of hormones and fertilization of eggs extracted from the woman and sperm from the man in the fluid while ICSI involves the extraction of sperm from the man and injecting a single sperm cell into an egg
  • IVF minimizes the risk of genetic disorder whereas, in ICSI the risk of conceiving with an embryo that has a genetic disorder is higher
  • IVF is suggested only when other methods of fertilization fail whereas ICSI is used when there is less sperm count

How effective is ICSI?

ICSI treatment is the most successful treatment for male infertility at present. The fertilization rate depends on the quality of the sperm used and the success rate depends on the cause of infertility issue and age.


The live birth rates for ICSI Treatment in Nepal are:

  • 65-75% for women aged below 35
  • 55-65% for women in the age group 35-37
  • 45-55% for women aged 38-40
  • 35-45% for women aged over 40

The success rate of taking the baby home using ISCI in Nepal in comparison with any developed countries is highest. ICSI offers you the benefit of having your own biological child even if other options failed. If your male partner faces difficulty in ejaculation, sperm can be manually extracted instead of eggs. Even the women suffering from severe Endometriosis, failed ovaries, poor ovarian reserve, unexplained infertility etc. are treated.

For More Details Please Contact Us

Venus IVF centre

Second floor-Venus hospital

Mid Baneshwor



Call: +977 984-1273668 , +977 1-4490333