When a person 40 years of age or older experiences infertility, IVF is occasionally suggested as the primary treatment. It could also be taken into consideration for particular medical issues. IVF is considered in the following cases

• If the fallopian tubes are damaged or obstructed, making it difficult to fertilize or implant the embryo, then infertility may be recommended. 

• Egg availability for fertilization is decreased as a result of ovulation problems. 
• Endometriosis is a condition that affects the reproductive organs when tissue resembling the uterine lining grows outside the uterus. 

• Embryo attachment is hampered by uterine fibroids, non-cancerous tumours that are typical in people in their 30s and 40s.
• Previous tubal ligation surgery necessitates an alternative method for conception.
• A specialist’s involvement is required since abnormalities in sperm inhibit conception. Despite diagnostic testing, infertility is still unaccounted for. 
• Preimplantation genetic testing is necessary since there is a chance of genetic abnormalities being passed on. 
• When undergoing cancer treatment or other medical procedures, it is desirable to preserve fertility so that frozen eggs or embryos can be used for future conception. 
• IVF with a gestational carrier may be selected in situations where there is a significant risk of pregnancy or where there is no functional uterus.